| Accession | TIGR01836 |
| Name | PHA_synth_III_C |
| Function | poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit |
| Gene Symbol | phaC |
| Trusted Cutoff | 365.30 |
| Domain Trusted Cutoff | 365.30 |
| Noise Cutoff | 174.75 |
| Domain Noise Cutoff | 174.75 |
| Isology Type | subfamily |
| HMM Length | 350 |
| Mainrole Category | Fatty acid and phospholipid metabolism |
| Subrole Category | Biosynthesis |
| Author | Haft DH |
| Entry Date | Feb 26 2003 12:15PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM represents the PhaC subunit of a heterodimeric form of polyhydroxyalkanoic acid (PHA) synthase. Excepting the PhaC of Bacillus megaterium (which needs PhaR), all members require PhaE (TIGR01834) for activity and are designated class III. This enzyme builds ester polymers for carbon and energy storage that accumulate in inclusions, and both this enzyme and the depolymerase associate with the inclusions. Class III enzymes polymerize short-chain-length hydroxyalkanoates. |
| References | RM 11418564
RT PhaC and PhaR are required for polyhydroxyalkanoic acid synthase activity in Bacillus megaterium.
RA McCool GJ, Cannon MC.
RL J Bacteriol 2001 Jul;183(14):4235-43 |
| Genome Property | GenProp0055: polyhydroxyalkanoic acids (HMM) |
