HMM Summary Page: TIGR01838

Functionpoly(R)-hydroxyalkanoic acid synthase, class I
Gene SymbolphaC
Trusted Cutoff622.65
Domain Trusted Cutoff622.65
Noise Cutoff532.45
Domain Noise Cutoff532.45
Isology Typesubfamily
HMM Length532
Mainrole CategoryFatty acid and phospholipid metabolism
Subrole CategoryBiosynthesis
AuthorHaft DH
Entry DateFeb 27 2003 1:19PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents the class I subfamily of poly(R)-hydroxyalkanoate synthases, which polymerizes hydroxyacyl-CoAs with three to five carbons in the hydroxyacyl backbone into aliphatic esters termed poly(R)-hydroxyalkanoic acids. These polymers accumulate as carbon and energy storage inclusions in many species and can amount to 90 percent of the dry weight of cell.
ReferencesRM 11418564 RT PhaC and PhaR are required for polyhydroxyalkanoic acid synthase activity in Bacillus megaterium. RA McCool GJ, Cannon MC. RL J Bacteriol 2001 Jul;183(14):4235-43
Genome PropertyGenProp0055: polyhydroxyalkanoic acids (HMM)