| Accession | TIGR01857 |
| Name | FGAM-synthase |
| Function | phosphoribosylformylglycinamidine synthase |
| Trusted Cutoff | 1057.05 |
| Domain Trusted Cutoff | 1057.05 |
| Noise Cutoff | 797.80 |
| Domain Noise Cutoff | 797.80 |
| Isology Type | equivalog |
| EC Number | 6.3.5.3 |
| HMM Length | 1239 |
| Mainrole Category | Purines, pyrimidines, nucleosides, and nucleotides |
| Subrole Category | Purine ribonucleotide biosynthesis |
| Gene Ontology Term | GO:0004642: phosphoribosylformylglycinamidine synthase activity molecular_function |
| | GO:0006189: 'de novo' IMP biosynthetic process biological_process |
| Author | Selengut J |
| Entry Date | Mar 21 2003 5:15PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM represents a single-molecule form of phosphoribosylformylglycinamidine synthase, also called FGAM synthase, an enzyme of purine de novo biosynthesis. This model represents a second clade of these enzymes found in Clostridia, Bifidobacteria and Streptococcus species. This enzyme performs the fourth step in IMP biosynthesis (the precursor of all purines) from PRPP. |
| Genome Property | GenProp0110: purine (inosine-5'-phosphate) biosynthesis from ribose-5-phosphate (HMM) |
| | GenProp0110: purine (inosine-5'-phosphate) biosynthesis from ribose-5-phosphate (HMM) |
| | GenProp0110: purine (inosine-5'-phosphate) biosynthesis from ribose-5-phosphate (HMM) |
