HMM Summary Page: TIGR01868

FunctionCRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI
Gene Symbolcas5e
Trusted Cutoff68.95
Domain Trusted Cutoff68.95
Noise Cutoff66.95
Domain Noise Cutoff66.95
Isology Typeequivalog
HMM Length230
Mainrole CategoryMobile and extrachromosomal element functions
Subrole CategoryOther
Gene Ontology TermGO:0003674: molecular_function molecular_function
GO:0043571: maintenance of CRISPR repeat elements biological_process
AuthorHaft DH
Entry DateApr 8 2003 10:49AM
Last ModifiedFeb 14 2011 3:27PM
CommentCRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is part of the ECOLI subtype CRISPR/Cas locus, and now characterized as part of the CASCADE complex of that system. It shares a small N-terminal homology region with members of several other CRISPR/Cas subtypes, and we view the families that share this region as being Cas5.
ReferencesDR URL DR URL RN [1] RT A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/cas subtypes exist in prokaryotic genomes RA Haft DH, Selengut JD, Mongodin EF, Nelsen KE RL PLOS Comput. Biol. 1(6), e60-e69, 2005
Genome PropertyGenProp0315: CRISPR system, I-E/Ecoli subtype (HMM)
GenProp0021: CRISPR region (HMM)