Accession | TIGR01966 |
Name | RNasePH |
Function | ribonuclease PH |
Gene Symbol | rph |
Trusted Cutoff | 141.50 |
Domain Trusted Cutoff | 141.50 |
Noise Cutoff | 117.35 |
Domain Noise Cutoff | 117.35 |
Isology Type | equivalog |
EC Number | 2.7.7.56 |
HMM Length | 236 |
Mainrole Category | Transcription |
Subrole Category | RNA processing |
Gene Ontology Term | GO:0004549: tRNA-specific ribonuclease activity molecular_function |
| GO:0008033: tRNA processing biological_process |
Author | Haft DH |
Entry Date | Aug 29 2003 10:18AM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This bacterial enzyme, ribonuclease PH, performs the final 3'-trimming and modification of tRNA precursors. This model is restricted absolutely to bacteria. Related families outside the model include proteins described as probable exosome complex exonucleases (rRNA processing) and polyribonucleotide nucleotidyltransferases (mRNA degradation). The most divergent member within the family is RNase PH from Deinococcus radiodurans. |
References | DR PROSITE; PS01277; Ribonuclease PH signature.
DR INTERPRO; IPR002381
DR HAMAP; MF_00564; 282 of 287 |