| Accession | TIGR01978 |
| Name | sufC |
| Function | FeS assembly ATPase SufC |
| Gene Symbol | sufC |
| Trusted Cutoff | 212.80 |
| Domain Trusted Cutoff | 212.80 |
| Noise Cutoff | 127.85 |
| Domain Noise Cutoff | 127.85 |
| Isology Type | equivalog |
| HMM Length | 243 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Other |
| Gene Ontology Term | GO:0005524: ATP binding molecular_function |
| | GO:0016226: iron-sulfur cluster assembly biological_process |
| Author | Haft DH |
| Entry Date | Sep 10 2003 2:25PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | SufC is part of the SUF system, shown in E. coli to consist of six proteins and believed to act in Fe-S cluster formation during oxidative stress. SufC forms a complex with SufB and SufD. SufC belongs to the ATP-binding cassette transporter family (PF00005) but is no longer thought to be part of a transporter. The complex is reported as cytosolic (PMID:12554644) or associated with the membrane (PMID:11943156). The SUF system also includes a cysteine desulfurase (SufS, enhanced by SufE) and a probable iron-sulfur cluster assembly scaffold protein, SufA. |
| Genome Property | GenProp0137: iron-sulfur cluster assembly SUF system (HMM) |
