HMM Summary Page: TIGR01979

Functioncysteine desulfurase, SufS family
Gene SymbolsufS
Trusted Cutoff475.10
Domain Trusted Cutoff475.10
Noise Cutoff352.70
Domain Noise Cutoff352.70
Isology Typesubfamily
HMM Length403
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryOther
Gene Ontology TermGO:0016226: iron-sulfur cluster assembly biological_process
GO:0031071: cysteine desulfurase activity molecular_function
AuthorHaft DH
Entry DateSep 10 2003 4:34PM
Last ModifiedMay 25 2011 6:05PM
CommentThis model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved.
ReferencesDR HAMAP; MF_01831; 29 of 30
Genome PropertyGenProp0137: iron-sulfur cluster assembly SUF system (HMM)