HMM Summary Page: TIGR01981

FunctionFeS assembly protein SufD
Gene SymbolsufD
Trusted Cutoff222.00
Domain Trusted Cutoff221.50
Noise Cutoff215.00
Domain Noise Cutoff215.00
Isology Typeequivalog
HMM Length275
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryOther
Gene Ontology TermGO:0005198: structural molecule activity molecular_function
GO:0016226: iron-sulfur cluster assembly biological_process
AuthorHaft DH
Entry DateSep 11 2003 1:11PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis protein, SufD, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation during oxidative stress. SufB and SufD are homologous. Note that SufC belongs to the family of ABC transporter ATP binding proteins, so this protein, encoded by an adjacent gene, has often been annotated as a transporter component.
Genome PropertyGenProp0137: iron-sulfur cluster assembly SUF system (HMM)