|Domain Trusted Cutoff||487.55|
|Domain Noise Cutoff||465.35|
|Mainrole Category||Biosynthesis of cofactors, prosthetic groups, and carriers|
|Subrole Category||Menaquinone and ubiquinone|
|Gene Ontology Term||GO:0006744: ubiquinone biosynthetic process biological_process|
| ||GO:0016709: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen molecular_function|
|Entry Date||Sep 11 2003 5:05PM|
|Last Modified||Feb 14 2011 3:27PM|
|Comment||This model represents the enzyme (UbiB) which catalyzes the first hydroxylation step in the ubiquinone biosynthetic pathway in bacteria [1,2]. It is believed that the reaction is 2-polyprenylphenol -> 6-hydroxy-2-polyprenylphenol. This model finds hits primarily in the proteobacteria. The gene is also known as AarF in certain species.|
RM PMID: 11583838
RT Ubiquinone biosynthesis in microorganisms.
RA Meganathan R.
RL FEMS Microbiol Lett. 2001 Sep 25;203(2):131-9.
RM PMID: 10960098
RT Identification of Escherichia coli ubiB, a gene required for the first monooxygenase step in ubiquinone biosynthesis.
RA Poon WW, Davis DE, Ha HT, Jonassen T, Rather PN, Clarke CF.
RL J Bacteriol. 2000 Sep;182(18):5139-46.
DR HAMAP; MF_00414; 87 of 89|
|Genome Property||GenProp0136: ubiquinone biosynthesis from chorismate, aerobic (HMM)|
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