HMM Summary Page: TIGR01986

Functionglutathione synthetase
Trusted Cutoff329.80
Domain Trusted Cutoff329.80
Noise Cutoff163.05
Domain Noise Cutoff163.05
Isology Typeequivalog
EC Number6.3.2.3
HMM Length473
Gene Ontology TermGO:0004363: glutathione synthase activity molecular_function
GO:0004363: glutathione synthase activity molecular_function
GO:0006750: glutathione biosynthetic process biological_process
GO:0006750: glutathione biosynthetic process biological_process
AuthorHaft DH
Entry DateSep 15 2003 5:33PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents the eukaryotic glutathione synthetase, which shows little resemblance to the analogous enzyme of Gram-negative bacteria (TIGR01380). In the Kinetoplastida, trypanothione replaces glutathione, but can be made from glutathione; a sequence from Leishmania is not included in the seed, is highly divergent, and therefore scores between the trusted and noise cutoffs.
Genome PropertyGenProp0030: glutathione biosynthesis (HMM)
GenProp0030: glutathione biosynthesis (HMM)