HMM Summary Page: TIGR01991

FunctionFe-S protein assembly chaperone HscA
Gene SymbolhscA
Trusted Cutoff708.55
Domain Trusted Cutoff708.55
Noise Cutoff668.45
Domain Noise Cutoff668.45
Isology Typeequivalog
HMM Length600
Mainrole CategoryProtein fate
Subrole CategoryProtein folding and stabilization
Gene Ontology TermGO:0005515: protein binding molecular_function
GO:0006457: protein folding biological_process
AuthorHaft DH
Entry DateSep 24 2003 4:13PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe Heat Shock Cognate proteins HscA and HscB act together as chaperones. HscA resembles DnaK but belongs in a separate clade. The apparent function is to aid assembly of iron-sulfur cluster proteins. Homologs from Buchnera and Wolbachia are clearly in the same clade but are highly derived and score lower than some examples of DnaK.
References DR HAMAP; MF_00679; 117 of 126
Genome PropertyGenProp0138: iron-sulfur cluster assembly iscSUA-hscBA-fdx system (HMM)