|Domain Trusted Cutoff||278.75|
|Domain Noise Cutoff||127.20|
|Mainrole Category||Energy metabolism|
|Subrole Category||Amino acids and amines|
|Gene Ontology Term||GO:0019557: histidine catabolic process to glutamate and formate biological_process|
| ||GO:0050129: N-formylglutamate deformylase activity molecular_function|
|Entry Date||Oct 14 2003 4:33PM|
|Last Modified||Feb 14 2011 3:27PM|
|Comment||In some species, histidine is converted to via urocanate and then formimino-L-glutamate to glutamate in four steps, where the fourth step is conversion of N-formimino-L-glutamate to L-glutamate and formamide. In others, that pathway from formimino-L-glutamate may differ, with the next enzyme being formiminoglutamate hydrolase (HutF) yielding N-formyl-L-glutamate. This HMM represents the enzyme N-formylglutamate deformylase, also called N-formylglutamate amidohydrolase, which then produces glutamate.|
RT Organization and multiple regulation of histidine utilization genes in Pseudomonas putida.
RA Hu L, Phillips AT.
RL J Bacteriol. 1988 Sep;170(9):4272-9.|
|Genome Property||GenProp0145: histidine degradation to glutamate (HMM)|
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