| Accession | TIGR02017 |
| Name | hutG_amidohyd |
| Function | N-formylglutamate deformylase |
| Gene Symbol | hutG |
| Trusted Cutoff | 278.75 |
| Domain Trusted Cutoff | 278.75 |
| Noise Cutoff | 127.20 |
| Domain Noise Cutoff | 127.20 |
| Isology Type | equivalog |
| EC Number | 3.5.1.68 |
| HMM Length | 263 |
| Mainrole Category | Energy metabolism |
| Subrole Category | Amino acids and amines |
| Gene Ontology Term | GO:0019557: histidine catabolic process to glutamate and formate biological_process |
| | GO:0050129: N-formylglutamate deformylase activity molecular_function |
| Author | Haft DH |
| Entry Date | Oct 14 2003 4:33PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | In some species, histidine is converted to via urocanate and then formimino-L-glutamate to glutamate in four steps, where the fourth step is conversion of N-formimino-L-glutamate to L-glutamate and formamide. In others, that pathway from formimino-L-glutamate may differ, with the next enzyme being formiminoglutamate hydrolase (HutF) yielding N-formyl-L-glutamate. This HMM represents the enzyme N-formylglutamate deformylase, also called N-formylglutamate amidohydrolase, which then produces glutamate. |
| References | RM 2842309
RT Organization and multiple regulation of histidine utilization genes in Pseudomonas putida.
RA Hu L, Phillips AT.
RL J Bacteriol. 1988 Sep;170(9):4272-9. |
| Genome Property | GenProp0145: histidine degradation to glutamate (HMM) |
