|Domain Trusted Cutoff||413.05|
|Domain Noise Cutoff||213.90|
|Mainrole Category||Energy metabolism|
|Subrole Category||Amino acids and amines|
|Gene Ontology Term||GO:0019557: histidine catabolic process to glutamate and formate biological_process|
| ||GO:0050416: formimidoylglutamate deiminase activity molecular_function|
|Entry Date||Oct 15 2003 2:57PM|
|Last Modified||Feb 14 2011 3:27PM|
|Comment||In some species, histidine utilization goes via urocanate to glutamate in four step, the last being removal of formamide. This HMM describes an alternate fourth step, formiminoglutamate hydrolase, which leads to N-formyl-L-glutamate. This product may be acted on by formylglutamate amidohydrolase (TIGR02017) and bypass glutamate as a product during its degradation. Alternatively, removal of formate (by EC 22.214.171.124) would yield glutamate.|
RT Organization and multiple regulation of histidine utilization genes in Pseudomonas putida.
RA Hu L, Phillips AT.
RL J Bacteriol. 1988 Sep;170(9):4272-9.|
|Genome Property||GenProp0145: histidine degradation to glutamate (HMM)|
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