HMM Summary Page: TIGR02042

Functionsulfite reductase, ferredoxin dependent
Gene Symbolsir
Trusted Cutoff731.50
Domain Trusted Cutoff731.50
Noise Cutoff574.70
Domain Noise Cutoff574.70
Isology Typeequivalog
EC Number1.8.7.1
HMM Length581
Mainrole CategoryCentral intermediary metabolism
Subrole CategorySulfur metabolism
Gene Ontology TermGO:0000103: sulfate assimilation biological_process
GO:0050311: sulfite reductase (ferredoxin) activity molecular_function
AuthorBrinkac L
Entry DateNov 3 2003 2:21PM
Last ModifiedFeb 14 2011 3:27PM
CommentDistantly related to the iron-sulfur hemoprotein of sulfite reductase (NADPH) found in Proteobacteria and Eubacteria, sulfite reductase (ferredoxin) is a cyanobacterial and plant monomeric enzyme that also catalyzes the reduction of sulfite to sulfide [1,2,3].
ReferencesRN [1] RM 8347657 RT The ferredoxin:sulphite reductase gene from Synechococcus PCC7942. RA Gisselmann G, Klausmeier P, Schwenn JD. RL Biochim Biophys Acta. 1993 Aug 16;1144(1):102-6. RN [2] RM 8695637 RT A cDNA clone from Arabidopsis thaliana encoding plastidic ferredoxin:sulfite reductase. RA Bruhl A, Haverkamp T, Gisselmann G, Schwenn JD. RL Biochim Biophys Acta. 1996 Jul 18;1295(2):119-24. RN [3] RM 9722674 RT Molecular characterization of tobacco sulfite reductase: enzyme purification, gene cloning, and gene expression analysis. RA Yonekura-Sakakibara K, Ashikari T, Tanaka Y, Kusumi T, Hase T. RL J Biochem (Tokyo). 1998 Sep;124(3):615-21. DR PFAM; PF01077; Nitrite and sulphite reductase 4Fe-4S domain DR PFAM; PF03460; Nitrite/Sulfite reductase ferredoxin-like half domain. DR EXPERIMENTAL; SP|P30008; Anacystis nidulans; expression using a fusion vector giving a single gene product immunologically related to the fd-sulphite reductase from the wild-type. DR EXPERIMENTAL GP|804953; Arabidopsis thaliana; enzymatically inactive expression of modified gene product; demonstrated specific cross-reaction with polyclonal antibodies against ferredoxin sulfite reductase from Synechococcus. DR EXPERIMENTAL; GP|3721540; Nicotiana tabacum; enzyme purification, gene cloning, and gene expression analysis. DR OUTGROUP; SP|P17846; Escherichia coli; Sulfite reductase [NADPH] hemoprotein beta-component.
Genome PropertyGenProp0149: sulfate reduction to sulfide, assimilatory (HMM)
GenProp0149: sulfate reduction to sulfide, assimilatory (HMM)