| Accession | TIGR02054 |
| Name | MerD |
| Function | mercuric resistence transcriptional repressor protein MerD |
| Gene Symbol | merD |
| Trusted Cutoff | 103.65 |
| Domain Trusted Cutoff | 103.65 |
| Noise Cutoff | 69.95 |
| Domain Noise Cutoff | 69.95 |
| Isology Type | equivalog |
| HMM Length | 120 |
| Mainrole Category | Cellular processes |
| Subrole Category | Detoxification |
| Gene Ontology Term | GO:0016564: transcription repressor activity molecular_function |
| | GO:0046689: response to mercury ion biological_process |
| Author | Selengut J |
| Entry Date | Nov 7 2003 4:03PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM represents a transcriptional repressor protein of the MerR family (PF00376) whose expression is regulated by the mercury-sensitive transcriptional activator, MerR. MerD has been shown to repress the transcription of the mer operon [1]. |
| References | RN [1]
RM PMID: 1917975
RT Purification and functional characterization of MerD. A coregulator of the mercury resistance operon in gram-negative bacteria.
RA Mukhopadhyay D, Yu HR, Nucifora G, Misra TK.
RL J Biol Chem. 1991 Oct 5;266(28):18538-42. |
| Genome Property | GenProp0151: resistance to mercury (HMM) |
