| Accession | TIGR02075 |
| Name | pyrH_bact |
| Function | UMP kinase |
| Gene Symbol | pyrH |
| Trusted Cutoff | 243.90 |
| Domain Trusted Cutoff | 243.90 |
| Noise Cutoff | 124.70 |
| Domain Noise Cutoff | 124.70 |
| Isology Type | equivalog |
| EC Number | 2.7.4.22 |
| HMM Length | 233 |
| Mainrole Category | Purines, pyrimidines, nucleosides, and nucleotides |
| Subrole Category | Nucleotide and nucleoside interconversions |
| Gene Ontology Term | GO:0015949: nucleobase-containing small molecule interconversion biological_process |
| | GO:0033862: UMP kinase activity molecular_function |
| Author | Haft DH |
| Entry Date | Dec 12 2003 12:05PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This protein, also called UMP kinase, converts UMP to UDP by adding a phosphate from ATP. It is the first step in pyrimidine biosynthesis. GTP is an allosteric activator. In a large fraction of all bacterial genomes, the gene tends to be located immediately downstream of elongation factor Ts and upstream of ribosome recycling factor. A related protein family, believed to be equivalent in function and found in the archaea and in spirochetes, is described by a separate model, TIGR02076. |
| References |
DR HAMAP; MF_01220; 492 of 538 |
