| Accession | TIGR02105 |
| Name | III_needle |
| Function | type III secretion apparatus needle protein |
| Gene Symbol | eprI |
| Trusted Cutoff | 41.70 |
| Domain Trusted Cutoff | 41.70 |
| Noise Cutoff | 28.25 |
| Domain Noise Cutoff | 28.25 |
| Isology Type | equivalog |
| HMM Length | 72 |
| Mainrole Category | Protein fate |
| Subrole Category | Protein and peptide secretion and trafficking |
| Gene Ontology Term | GO:0030254: protein secretion by the type III secretion system biological_process |
| Author | Haft DH |
| Entry Date | Jan 20 2004 5:26PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Type III secretion systems translocate proteins, usually virulence factors, out across both inner and outer membranes of certain Gram-negative bacteria and further across the plasma membrane and into the cytoplasm of the host cell. This protein, termed YscF in Yersinia, and EscF, PscF, EprI, etc. in other systems, forms the needle of the injection apparatus. |
| References | RM 14580388
RT Genetic analysis of the formation of the Ysc-Yop translocation pore in macrophages by Yersinia enterocolitica: role of LcrV, YscF and YopN.
RA Marenne MN, Journet L, Mota LJ, Cornelis GR.
RL Microb Pathog. 2003 Dec; 35(6): 243-58.
DR EXPERIMENTAL; SP|Q01247; Yersinia enterocolitica plasmid pYV |
| Genome Property | GenProp0052: type III secretion (HMM) |
