HMM Summary Page: TIGR02107

Functioncoenzyme PQQ precursor peptide PqqA
Gene SymbolpqqA
Trusted Cutoff20.00
Domain Trusted Cutoff20.00
Noise Cutoff19.00
Domain Noise Cutoff16.00
Isology Typeequivalog
HMM Length21
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryOther
Gene Ontology TermGO:0003824: catalytic activity molecular_function
GO:0018189: pyrroloquinoline quinone biosynthetic process biological_process
AuthorHaft DH
Entry DateJan 21 2004 4:12PM
Last ModifiedApr 26 2011 12:26PM
CommentThis HMM describes a very small protein, coenzyme PQQ biosynthesis protein A, which is smaller than 25 amino acids in many species. It is proposed to serve as a peptide precursor of coenzyme pyrrolo-quinoline-quinone (PQQ), with Glu and Tyr of a conserved motif Glu-Xxx-Xxx-Xxx-Tyr becoming part of the product.
ReferencesRM 9467911 RT pqqA is not required for biosynthesis of pyrroloquinoline quinone in Methylobacterium extorquens AM1. RA Toyama H, Lidstrom ME. TL Microbiology. 1998 Jan; 144 ( Pt 1): 183-91. DR HAMAP; MF_00656; 28 of 28
Genome PropertyGenProp0170: coenzyme PQQ biosynthesis (HMM)