HMM Summary Page: TIGR02109

Functioncoenzyme PQQ biosynthesis enzyme PqqE
Gene SymbolpqqE
Trusted Cutoff381.35
Domain Trusted Cutoff381.35
Noise Cutoff174.15
Domain Noise Cutoff174.15
Isology Typeequivalog
HMM Length358
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryOther
Gene Ontology TermGO:0018189: pyrroloquinoline quinone biosynthetic process biological_process
AuthorHaft DH
Entry DateJan 22 2004 1:07PM
Last ModifiedApr 26 2011 12:30PM
CommentThis HMM describes coenzyme PQQ biosynthesis protein E, a prototypical peptide-cyclizing radical SAM enzyme. It links a Tyr to a Glu as the first step in the biosynthesis of pyrrolo-quinoline-quinone (coenzyme PQQ) from the precursor peptide PqqA. PQQ is required for some glucose dehydrogenases and alcohol dehydrogenases.
ReferencesDR HAMAP; MF_00660; 29 of 29
Genome PropertyGenProp0170: coenzyme PQQ biosynthesis (HMM)