| Accession | TIGR02116 |
| Name | toxin_Txe_YoeB |
| Function | addiction module toxin, Txe/YoeB family |
| Trusted Cutoff | 51.80 |
| Domain Trusted Cutoff | 51.80 |
| Noise Cutoff | 41.60 |
| Domain Noise Cutoff | 41.60 |
| Isology Type | equivalog |
| HMM Length | 80 |
| Mainrole Category | Cellular processes |
| Subrole Category | Toxin production and resistance |
| Gene Ontology Term | GO:0008219: cell death biological_process |
| Author | Haft DH |
| Entry Date | Jan 29 2004 3:03PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | The Axe-Txe pair in Enterococcus faecium and the homologous YefM-YoeB pair in Escherichia coli have been shown to act as an antitoxin-toxin pair. This HMM describes the toxin component. Nearly every example found is next to an identifiable antitoxin, as indicated by match to HMMs TIGR01552 and/or PF02604. |
| References | RM 12603745
RT Axe-Txe, a broad-spectrum proteic toxin-antitoxin system specified by a multidrug-resistant, clinical isolate of Enterococcus faecium.
RA Grady R, Hayes F.
RL Mol Microbiol. 2003 Mar; 47(5): 1419-32. |
| Genome Property | GenProp0321: addiction modules (HMM) |
