HMM Summary Page: TIGR02141

AccessionTIGR02141
NamemodB_ABC
Functionmolybdate ABC transporter, permease protein
Gene SymbolmodB
Trusted Cutoff182.60
Domain Trusted Cutoff182.60
Noise Cutoff181.85
Domain Noise Cutoff181.85
Isology Typeequivalog
HMM Length208
Mainrole CategoryTransport and binding proteins
Subrole CategoryAnions
Gene Ontology TermGO:0005887: integral to plasma membrane cellular_component
GO:0015412: molybdate transmembrane-transporting ATPase activity molecular_function
GO:0015689: molybdate ion transport biological_process
GO:0055052: ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing cellular_component
AuthorSelengut J, Haft DH
Entry DateMar 5 2004 9:04AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM describes the permease protein, ModB, of the molybdate ABC transporter. This system has been characterized in E. coli [1], Staphylococcus carnosus [2] Rhodobacter capsulatus [3] and Azotobacter vinlandii [4]. Molybdate is chemically similar to sulfate, thiosulfate, and selenate. These related substrates, and sometimes molybdate itself, can be transported by the homologous sulfate receptor. Some apparent molybdenum transport operons include a permease related to this ModB, although less similar than some sulfate permease proteins and not included in this model.
ReferencesRN [1] RM PMID: 7665460 RT Genetic analysis of the modABCD (molybdate transport) operon of Escherichia coli. RA Maupin-Furlow JA, Rosentel JK, Lee JH, Deppenmeier U, Gunsalus RP, Shanmugam KT. RL J Bacteriol 1995 Sep;177(17):4851-6 RN [2] RM PMID: 10415172 RT Characterization of the molybdate transport system ModABC of Staphylococcus carnosus. RA Neubauer H, Pantel I, Lindgren PE, Gotz F. RL Arch Microbiol 1999 Aug;172(2):109-15 RN [3] RM PMID: 8491722 RT Characterization of Rhodobacter capsulatus genes encoding a molybdenum transport system and putative molybdenum-pterin-binding proteins. RA Wang G, Angermuller S, Klipp W. RL J Bacteriol 1993 May;175(10):3031-42 RN [4] RM PMID: 7665518 RT Mutational analysis of genes of the mod locus involved in molybdenum transport, homeostasis, and processing in Azotobacter vinelandii. RA Mouncey NJ, Mitchenall LA, Pau RN. RL J Bacteriol 1995 Sep;177(18):5294-302.
Genome PropertyGenProp0192: molybdate ABC transporter (HMM)