| Accession | TIGR02154 |
| Name | PhoB |
| Function | phosphate regulon transcriptional regulatory protein PhoB |
| Gene Symbol | phoB |
| Trusted Cutoff | 296.20 |
| Domain Trusted Cutoff | 296.20 |
| Noise Cutoff | 260.85 |
| Domain Noise Cutoff | 260.85 |
| Isology Type | equivalog |
| HMM Length | 226 |
| Mainrole Category | Regulatory functions |
| Subrole Category | DNA interactions |
| Gene Ontology Term | GO:0000156: two-component response regulator activity molecular_function |
| | GO:0000160: two-component signal transduction system (phosphorelay) biological_process |
| | GO:0003700: sequence-specific DNA binding transcription factor activity molecular_function |
| | GO:0006355: regulation of transcription, DNA-dependent biological_process |
| | GO:0006796: phosphate-containing compound metabolic process biological_process |
| Author | Selengut J |
| Entry Date | Apr 2 2004 11:38AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | PhoB is a DNA-binding response regulator protein acting with PhoR in a 2-component system responding to phosphate ion. PhoB acts as a positive regulator of gene expression for phosphate-related genes such as phoA, phoS, phoE and ugpAB as well as itself [1]. It is often found proximal to genes for the high-affinity phosphate ABC transporter (pstSCAB; GenProp0190) and presumably regulates these as well. |
| References | RN [1]
RM PMID: 3537313
RT Nucleotide sequence of the phoB gene, the positive regulatory gene for the phosphate regulon of Escherichia coli K-12.
RA Makino K, Shinagawa H, Amemura M, Nakata A.
RL J Mol Biol. 1986 Jul 5;190(1):37-44. |
| Genome Property | GenProp0190: phosphate ABC transporter (pstSCAB-phoU) (HMM) |
