HMM Summary Page: TIGR02188

Functionacetate--CoA ligase
Gene Symbolacs
Trusted Cutoff724.95
Domain Trusted Cutoff724.95
Noise Cutoff684.65
Domain Noise Cutoff684.65
Isology Typeequivalog
EC Number6.2.1.1
HMM Length629
Gene Ontology TermGO:0003987: acetate-CoA ligase activity molecular_function
GO:0019427: acetyl-CoA biosynthetic process from acetate biological_process
AuthorHaft DH
Entry DateMay 12 2004 10:30AM
Last ModifiedOct 30 2011 7:20PM
CommentThis HMM describes acetate-CoA ligase (EC, also called acetyl-CoA synthetase and acetyl-activating enzyme. It catalyzes the reaction ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA and belongs to the family of AMP-binding enzymes described by Pfam model PF00501.
ReferencesDR PFAM; PF00501; AMP-binding DR PROSITE; PS00455; AMP_BINDING DR IPR000873; AMP-bind DR HAMAP; MF_01123; 134 of 136
Genome PropertyGenProp0480: acetyl-CoA biosynthesis from acetate, direct (HMM)