| Accession | TIGR02188 |
| Name | Ac_CoA_lig_AcsA |
| Function | acetate--CoA ligase |
| Gene Symbol | acs |
| Trusted Cutoff | 724.95 |
| Domain Trusted Cutoff | 724.95 |
| Noise Cutoff | 684.65 |
| Domain Noise Cutoff | 684.65 |
| Isology Type | equivalog |
| EC Number | 6.2.1.1 |
| HMM Length | 629 |
| Gene Ontology Term | GO:0003987: acetate-CoA ligase activity molecular_function |
| | GO:0019427: acetyl-CoA biosynthetic process from acetate biological_process |
| Author | Haft DH |
| Entry Date | May 12 2004 10:30AM |
| Last Modified | Oct 30 2011 7:20PM |
| Comment | This HMM describes acetate-CoA ligase (EC 6.2.1.1), also called acetyl-CoA synthetase and acetyl-activating enzyme. It catalyzes the reaction ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA and belongs to the family of AMP-binding enzymes described by Pfam model PF00501. |
| References | DR PFAM; PF00501; AMP-binding
DR PROSITE; PS00455; AMP_BINDING
DR IPR000873; AMP-bind
DR HAMAP; MF_01123; 134 of 136 |
| Genome Property | GenProp0480: acetyl-CoA biosynthesis from acetate, direct (HMM) |