Accession | TIGR02212 |
Name | lolCE |
Function | lipoprotein releasing system, transmembrane protein, LolC/E family |
Trusted Cutoff | 362.45 |
Domain Trusted Cutoff | 362.45 |
Noise Cutoff | 242.10 |
Domain Noise Cutoff | 242.10 |
Isology Type | subfamily |
HMM Length | 411 |
Mainrole Category | Protein fate |
Subrole Category | Protein and peptide secretion and trafficking |
Gene Ontology Term | GO:0005887: integral to plasma membrane cellular_component |
| GO:0042953: lipoprotein transport biological_process |
| GO:0042954: lipoprotein transporter activity molecular_function |
Author | Haft DH |
Entry Date | May 26 2004 5:08PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This HMM describes the LolC protein, and its paralog LolE found in some species. These proteins are homologous to permease proteins of ABC transporters. In some species, two paralogs occur, designated LolC and LolE. In others, a single form is found and tends to be designated LolC. |
References | DR PFAM; PF02687; FtsX
RM 12823819
RT A mutation in the membrane subunit of an ABC transporter LolCDE complex causing outer membrane localization of lipoproteins against their inner membrane-specific signals.
RA Narita S, Kanamaru K, Matsuyama S, Tokuda H.
RL Mol Microbiol. 2003 Jul;49(1):167-77. |
Genome Property | GenProp0207: lipoprotein localization system lolABCDE (HMM) |