HMM Summary Page: TIGR02223

AccessionTIGR02223
NameftsN
Functioncell division protein FtsN
Gene SymbolftsN
Trusted Cutoff107.65
Domain Trusted Cutoff107.65
Noise Cutoff65.55
Domain Noise Cutoff65.55
Isology Typeequivalog
HMM Length299
Mainrole CategoryCellular processes
Subrole CategoryCell division
Gene Ontology TermGO:0000910: cytokinesis biological_process
AuthorHaft DH
Entry DateJun 14 2004 12:19PM
Last ModifiedFeb 14 2011 3:27PM
CommentFtsN is a poorly conserved protein active in cell division in a number of Proteobacteria. The N-terminal 30 residue region tends to by Lys/Arg-rich, and is followed by a membrane-spanning region. This is followed by an acidic low-complexity region of variable length and a well-conserved C-terminal domain of two tandem regions matched by Pfam model PF05036 (Sporulation related repeat), found in several cell division and sporulation proteins. The role of FtsN as a suppressor for other cell division mutations is poorly understood; it may involve cell wall hydrolysis.
ReferencesDR PFAM; PF05036; Sporulation related repeat RN [1] RM 12626683 RT Cytokinesis in bacteria. RA Errington J, Daniel RA, Scheffers DJ. RL Microbiol Mol Biol Rev. 2003 Mar;67(1):52-65
Genome PropertyGenProp0206: bacterial cell division septum system (HMM)