HMM Summary Page: TIGR02223

Functioncell division protein FtsN
Gene SymbolftsN
Trusted Cutoff107.65
Domain Trusted Cutoff107.65
Noise Cutoff65.55
Domain Noise Cutoff65.55
Isology Typeequivalog
HMM Length299
Mainrole CategoryCellular processes
Subrole CategoryCell division
Gene Ontology TermGO:0000910: cytokinesis biological_process
AuthorHaft DH
Entry DateJun 14 2004 12:19PM
Last ModifiedFeb 14 2011 3:27PM
CommentFtsN is a poorly conserved protein active in cell division in a number of Proteobacteria. The N-terminal 30 residue region tends to by Lys/Arg-rich, and is followed by a membrane-spanning region. This is followed by an acidic low-complexity region of variable length and a well-conserved C-terminal domain of two tandem regions matched by Pfam model PF05036 (Sporulation related repeat), found in several cell division and sporulation proteins. The role of FtsN as a suppressor for other cell division mutations is poorly understood; it may involve cell wall hydrolysis.
ReferencesDR PFAM; PF05036; Sporulation related repeat RN [1] RM 12626683 RT Cytokinesis in bacteria. RA Errington J, Daniel RA, Scheffers DJ. RL Microbiol Mol Biol Rev. 2003 Mar;67(1):52-65
Genome PropertyGenProp0206: bacterial cell division septum system (HMM)