|Function||3-hydroxyacyl-CoA dehydrogenase PaaC|
|Domain Trusted Cutoff||669.40|
|Domain Noise Cutoff||593.65|
|Entry Date||Aug 31 2004 12:56PM|
|Last Modified||Feb 14 2011 3:27PM|
|Comment||This 3-hydroxyacyl-CoA dehydrogenase is involved in the degradation of phenylacetic acid, presumably in steps following the opening of the phenyl ring . The sequences included in this model are all found in aparrent operons with other related genes such as paaA, paaB, paaD, paaE, paaF and paaN . Some genomes contain these other genes without an apparent paaC in the same operon - possibly in these cases a different dehydrogenase involved in fatty acid degradation may fill in the needed activity. This enzyme has domains which are members of the PF02737 and PF00725 families.|
RM PMID: 9748275
RT Catabolism of phenylacetic acid in Escherichia coli. Characterization of a new aerobic hybrid pathway.
RA Ferrandez A, Minambres B, Garcia B, Olivera ER, Luengo JM, Garcia JL, Diaz E.
RL J Biol Chem. 1998 Oct 2;273(40):25974-86.
RM PMID: 11260461
RT The phenylacetyl-CoA catabolon: a complex catabolic unit with broad biotechnological applications.
RA Luengo JM, Garcia JL, Olivera ER.
RL Mol Microbiol. 2001 Mar;39(6):1434-42.|
|Genome Property||GenProp0210: phenylacetic acid catabolism (HMM)|
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