|Function||phenylacetate degradation probable enoyl-CoA hydratase PaaB|
|Domain Trusted Cutoff||345.15|
|Domain Noise Cutoff||303.40|
|Gene Ontology Term||GO:0004300: enoyl-CoA hydratase activity molecular_function|
| ||GO:0010124: phenylacetate catabolic process biological_process|
|Entry Date||Aug 31 2004 2:49PM|
|Last Modified||Mar 1 2011 11:50AM|
|Comment||This family of proteins are found within apparent operons for the degradation of phenylacetic acid . These proteins contain the enoyl-CoA hydratase domain as detected by PF00378. This activity is consistent with current hypotheses for the degradation pathway  which involve the ligation of phenylacetate with coenzyme A (paaF), hydroxylation (paaGHIJK), ring-opening (paaN) and degradation of the resulting fatty acid-like compound to a Krebs cycle intermediate (paaABCDE).|
RM PMID: 11260461
RT The phenylacetyl-CoA catabolon: a complex catabolic unit with broad biotechnological applications.
RA Luengo JM, Garcia JL, Olivera ER.
RL Mol Microbiol. 2001 Mar;39(6):1434-42.
RM PMID: 9748275
RT Catabolism of phenylacetic acid in Escherichia coli. Characterization of a new aerobic hybrid pathway.
RA Ferrandez A, Minambres B, Garcia B, Olivera ER, Luengo JM, Garcia JL, Diaz E.
RL J Biol Chem. 1998 Oct 2;273(40):25974-86.|
|Genome Property||GenProp0210: phenylacetic acid catabolism (HMM)|
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