|Function||5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase|
|Domain Trusted Cutoff||638.35|
|Domain Noise Cutoff||593.45|
|Entry Date||Sep 13 2004 11:59AM|
|Last Modified||Feb 14 2011 3:27PM|
|Comment||This model represents the dehydrogenase responsible for the conversion of 5-carboxymethyl-2-hydroxymuconate semialdehyde to 5-carboxymethyl-2-hydroxymuconate (a tricarboxylic acid). This is the step in the degradation of 4-hydroxyphenylacetic acid via homoprotocatechuate following the oxidative opening of the aromatic ring.|
RM PMID: 2194577
RT Nucleotide sequences of the meta-cleavage pathway enzymes 2-hydroxymuconic semialdehyde dehydrogenase and 2-hydroxymuconic semialdehyde hydrolase from Pseudomonas CF600.
RA Nordlund I, Shingler V.
RL Biochim Biophys Acta. 1990 Jun 21;1049(2):227-30.|
|Genome Property||GenProp0231: 4-hydroxyphenylacetate degradation (HMM)|
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