HMM Summary Page: TIGR02316
Accession | TIGR02316 |
Name | propion_prpE |
Function | propionate--CoA ligase |
Gene Symbol | prpE |
Trusted Cutoff | 827.40 |
Domain Trusted Cutoff | 827.40 |
Noise Cutoff | 760.80 |
Domain Noise Cutoff | 760.80 |
Isology Type | equivalog |
EC Number | 6.2.1.17 |
HMM Length | 628 |
Author | Haft DH |
Entry Date | Sep 24 2004 3:32PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This family contains one of three readily separable clades of proteins in the group of acetate and propionate--CoA ligases. Characterized members of this family act on propionate. From propionyl-CoA, there is a cyclic degradation pathway: it is ligated by PrpC to the TCA cycle intermediate oxaloacetate, acted upon further by PrpD and an aconitase, then cleaved by PrpB to pyruvate and the TCA cycle intermediate succinate. |