|Function||phosphonate C-P lyase system protein PhnL|
|Domain Trusted Cutoff||256.30|
|Domain Noise Cutoff||153.25|
|Gene Ontology Term||GO:0018835: carbon phosphorus lyase activity molecular_function|
| ||GO:0019634: organic phosphonate metabolic process biological_process|
|Entry Date||Sep 28 2004 3:09PM|
|Last Modified||Feb 14 2011 3:27PM|
|Comment||Members of this family are the PhnL protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated C-P lysase complex. This protein (PhnL) and the adjacent-encoded PhnK (TIGR02323) resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this C-P lyase complex rather than part of a transporter per se.|
RT Mutational analysis of an Escherichia coli fourteen-gene operon for phosphonate degradation, using TnphoA' elements.
RA Metcalf WW, Wanner BL.
RL J Bacteriol. 1993 Jun;175(11):3430-42.|
|Genome Property||GenProp0232: phosphonates C-P lyase system (HMM)|
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