| Accession | TIGR02460 |
| Name | osmo_MPGsynth |
| Function | mannosyl-3-phosphoglycerate synthase |
| Gene Symbol | mpgS |
| Trusted Cutoff | 351.20 |
| Domain Trusted Cutoff | 351.20 |
| Noise Cutoff | 132.00 |
| Domain Noise Cutoff | 132.00 |
| Isology Type | equivalog |
| EC Number | 2.4.1.217 |
| HMM Length | 383 |
| Gene Ontology Term | GO:0050504: mannosyl-3-phosphoglycerate synthase activity molecular_function |
| Author | Haft DH |
| Entry Date | Feb 4 2005 10:37AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This family consists of examples of mannosyl-3-phosphoglycerate synthase (MPGS), which together mannosyl-3-phosphoglycerate phosphatase (MPGP) comprises a two-step pathway for mannosylglycerate biosynthesis. Mannosylglycerate is a compatible solute that tends to be restricted to extreme thermophiles of archaea and bacteria. Note that in Rhodothermus marinus, this pathway is one of two; the other is condensation of GDP-mannose with D-glycerate by mannosylglycerate synthase. |
| References | RN [1]
RM 12788726
RT The bacterium Thermus thermophilus, like hyperthermophilic archaea, uses a two-step pathway for the synthesis of mannosylglycerate.
RA Empadinhas N, Albuquerque L, Henne A, Santos H, da Costa MS.
RL Appl Environ Microbiol. 2003 Jun;69(6):3272-9. |
| Genome Property | GenProp0281: mannosylglycerate biosynthesis (HMM) |