HMM Summary Page: TIGR02509
Accession | TIGR02509 |
Name | type_III_yopR |
Function | type III secretion effector, YopR family |
Trusted Cutoff | 114.00 |
Domain Trusted Cutoff | 114.00 |
Noise Cutoff | 55.25 |
Domain Noise Cutoff | 55.25 |
Isology Type | equivalog |
HMM Length | 131 |
Mainrole Category | Cellular processes |
Subrole Category | Pathogenesis |
Author | Haft DH |
Entry Date | Mar 7 2005 5:27PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | Members of this family are type III secretion system effectors, named differently in different species and designated YopR (Yersinia outer protein R), encoded by the YscH (Yersinia secretion H) gene. This Yops protein is unusual in that it is released to extracellularly rather than injected directly into the target cell as are most Yops. |
References | RN [1] RM 10209737 RT Type III machines of pathogenic yersiniae secrete virulence factors into the extracellular milieu. RA Lee VT, Schneewind O. RL Mol Microbiol. 1999 Mar;31(6):1619-29. RN [2] RM 8709853 RT Mutational analysis of the Yersinia enterocolitica virC operon: characterization of yscE, F, G, I, J, K required for Yop secretion and yscH encoding YopR. RA Allaoui A, Schulte R, Cornelis GR. RL Mol Microbiol. 1995 Oct;18(2):343-55. |
Genome Property | GenProp0052: type III secretion (HMM) |