|Function||[FeFe] hydrogenase, group A|
|Domain Trusted Cutoff||405.95|
|Domain Noise Cutoff||300.65|
|Entry Date||Mar 8 2005 4:26PM|
|Last Modified||Feb 14 2011 3:27PM|
|Comment||This model describes iron-only hydrogenases of anaerobic and microaerophilic bacteria and protozoa. This model is narrower, and covers a longer stretch of sequence, than Pfam model PF02906. This family represents a division among families that belong to PF02906, which also includes proteins such as nuclear prelamin A recognition factor in animals. Note that this family shows some heterogeneity in terms of periplasmic, cytosolic, or hydrogenosome location, NAD or NADP dependence, and overal protein protein length.|
|References||DR PFAM; PF02906; Fe_hyd_lg_C
RT Iron hydrogenases and the evolution of anaerobic eukaryotes.
RA Horner DS, Foster PG, Embley TM.
RL Mol Biol Evol. 2000 Nov;17(11):1695-709.
RT The surprising diversity of clostridial hydrogenases: a comparative genomic perspective.
RA Calusinska M, Happe T, Joris B, Wilmotte A
RL Microbiology. 2010 Jun;156(Pt 6):1575-88.|
|Genome Property||GenProp0914: hydrogenase, [FeFe]-dependent (HMM)|
| ||GenProp0914: hydrogenase, [FeFe]-dependent (HMM)|
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