| Accession | TIGR02551 |
| Name | SpaO_YscQ |
| Function | type III secretion apparatus protein, YscQ/HrcQ family |
| Gene Symbol | epaO |
| Trusted Cutoff | 100.80 |
| Domain Trusted Cutoff | 100.80 |
| Noise Cutoff | 79.00 |
| Domain Noise Cutoff | 79.00 |
| Isology Type | equivalog |
| HMM Length | 300 |
| Mainrole Category | Protein fate |
| Subrole Category | Protein and peptide secretion and trafficking |
| Gene Ontology Term | GO:0009405: pathogenesis biological_process |
| | GO:0030254: protein secretion by the type III secretion system biological_process |
| | GO:0030257: type III protein secretion system complex cellular_component |
| Author | Selengut J |
| Entry Date | Apr 18 2005 1:18PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Genes in this family are found in type III secretion operons. The gene (YscQ) in Yersinia is essential for YOPs secretion [1], while SpaO in Shigella is involved in the Surface Presentation of Antigens apparatus found on the virulence plasmid [2], and HrcQ is involved in the Harpin secretory system in organisms like Pseudomonas syringae [3]. |
| References | RN [1]
RM PMID: 8169210
RT The lcrB (yscN/U) gene cluster of Yersinia pseudotuberculosis is involved in Yop secretion and shows high homology to the spa gene clusters of Shigella flexneri and Salmonella typhimurium.
RA Bergman T, Erickson K, Galyov E, Persson C, Wolf-Watz H.
RL J Bacteriol. 1994 May;176(9):2619-26.
RN [2]
RM PMID: 8404849
RT Cognate gene clusters govern invasion of host epithelial cells by Salmonella typhimurium and Shigella flexneri.
RA Groisman EA, Ochman H.
RL EMBO J. 1993 Oct;12(10):3779-87.
RN [3]
RM PMID: 9721292
RT Negative regulation of hrp genes in Pseudomonas syringae by HrpV.
RA Preston G, Deng WL, Huang HC, Collmer A.
RL J Bacteriol. 1998 Sep;180(17):4532-7. |
| Genome Property | GenProp0052: type III secretion (HMM) |
