HMM Summary Page: TIGR02573

Functiontype III secretion protein LcrG
Trusted Cutoff90.80
Domain Trusted Cutoff90.80
Noise Cutoff51.40
Domain Noise Cutoff51.40
Isology Typeequivalog
HMM Length90
AuthorSelengut J
Entry DateMay 2 2005 12:47PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis protein is found in type III secretion operons, along with LcrR, H and V. Also known as PcrG in Pseudomonas, the protein is believed to make a 1:1 complex with PcrV (LcrV) [1]. Mutants of LcrG cause premature secretion of effector proteins into the medium [2].
ReferencesRN [1] RM PMID: 14565848 RT Type III secretion proteins PcrV and PcrG from Pseudomonas aeruginosa form a 1:1 complex through high affinity interactions. RA Nanao M, Ricard-Blum S, Di Guilmi AM, Lemaire D, Lascoux D, Chabert J, Attree I, Dessen A. RL BMC Microbiol. 2003 Oct 18;3(1):21. RN [2] RM PMID: 11443094 RT Roles of LcrG and LcrV during type III targeting of effector Yops by Yersinia enterocolitica. RA DeBord KL, Lee VT, Schneewind O. RL J Bacteriol. 2001 Aug;183(15):4588-98.
Genome PropertyGenProp0052: type III secretion (HMM)