| Accession | TIGR02593 |
| Name | CRISPR_cas5 |
| Function | CRISPR-associated protein Cas5 |
| Gene Symbol | cas5 |
| Trusted Cutoff | 17.80 |
| Domain Trusted Cutoff | 15.00 |
| Noise Cutoff | 15.80 |
| Domain Noise Cutoff | 14.00 |
| Isology Type | subfamily_domain |
| HMM Length | 43 |
| Mainrole Category | Mobile and extrachromosomal element functions |
| Subrole Category | Other |
| Gene Ontology Term | GO:0003674: molecular_function molecular_function |
| | GO:0043571: maintenance of CRISPR repeat elements biological_process |
| Author | Haft DH |
| Entry Date | May 31 2005 9:43AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This model represents a shared N-terminal domain, about 43 amino acids in length, common to a number of related protein families each of which is associated with a distinct subtype of CRISPR/cas system, where CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeat and Cas is an abbreviation for CRISPR-associated. Members of this family are widely distributed enough that we designated the family Cas5. Homology appears remote, or absent, between the more C-terminal regions different subfamilies of these proteins, which typically are 210 to 265 amino acids in total length. Cas5 proteins of six different CRISPR/cas subtypes so far defined are described by respective full-length models TIGR01868, TIGR01876, TIGR01895, TIGR01874, TIGR02586, and TIGR02592. The best characterized protein in this family is DevS or Myxococcus xanthus, a Cas protein that appears to participate in a species-specific developmental pathway. |
| References | DR URL http://www.tigr.org/tigr-scripts/CMR2/genome_property_def.spl?prop=2003
RN [1]
RT A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/cas subtypes exist in prokaryotic genomes
RA Haft DH, Selengut JD, Mongodin EF, Nelsen KE
RL PLOS Comput. Biol. 1(6), e60-e69, 2005 |
| Genome Property | GenProp0021: CRISPR region (HMM) |
