|Function||circadian clock protein KaiC|
|Domain Trusted Cutoff||546.25|
|Domain Noise Cutoff||364.05|
|Mainrole Category||Cellular processes|
|Gene Ontology Term||GO:0004674: protein serine/threonine kinase activity molecular_function|
| ||GO:0007623: circadian rhythm biological_process|
| ||GO:0016564: transcription repressor activity molecular_function|
| ||GO:0046777: protein autophosphorylation biological_process|
|Entry Date||Sep 7 2005 12:42PM|
|Last Modified||Feb 14 2011 3:27PM|
|Comment||Members of this family are the circadian clock protein KaiC, part of the kaiABC operon that controls circadian rhythm. It may be universal in Cyanobacteria. Each member has two copies of the KaiC domain (Pfam model PF06745), which is also found in other proteins. KaiC performs autophosphorylation and acts as its own transcriptional repressor.|
|References||DR PFAM; PF06745; KaiC
RT Role of KaiC phosphorylation in the circadian clock system of Synechococcus elongatus PCC 7942.
RA Nishiwaki T, Satomi Y, Nakajima M, Lee C, Kiyohara R, Kageyama H, Kitayama Y, Temamoto M, Yamaguchi A, Hijikata A, Go M, Iwasaki H, Takao T, Kondo T.
RL Proc Natl Acad Sci U S A. 2004 Sep 21;101(38):13927-32.
DR HAMAP; MF_01836; 13 of 13|
|Genome Property||GenProp0465: circadian clock system KaiABC (HMM)|
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