|Domain Trusted Cutoff||462.90|
|Domain Noise Cutoff||400.20|
|Mainrole Category||Biosynthesis of cofactors, prosthetic groups, and carriers|
|Gene Ontology Term||GO:0004410: homocitrate synthase activity molecular_function|
| ||GO:0051188: cofactor biosynthetic process biological_process|
|Entry Date||Sep 9 2005 8:30AM|
|Last Modified||Feb 14 2011 3:27PM|
|Comment||This family consists of the NifV clade of homocitrate synthases, most of which are found in operons for nitrogen fixation. Members are closely homologous to enzymes that include 2-isopropylmalate synthase, (R)-citramalate synthase, and homocitrate synthases associated with other processes. The homocitrate made by this enzyme becomes a part of the iron-molybdenum cofactor of nitrogenase.|
RT Purification of the Azotobacter vinelandii nifV-encoded homocitrate synthase.
RA Zheng L, White RH, Dean DR.
RL J Bacteriol. 1997 Sep;179(18):5963-6.
RT Molecular cloning and complementation analysis of nifV gene from Frankia EuIK1 strain.
RA Oh CJ, Kim HB, An CS.
RL Mol Cells. 2003 Feb 28;15(1):27-33.|
|Genome Property||GenProp0029: nitrogen fixation (HMM)|
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