| Accession | TIGR02660 |
| Name | nifV_homocitr |
| Function | homocitrate synthase |
| Gene Symbol | nifV |
| Trusted Cutoff | 462.90 |
| Domain Trusted Cutoff | 462.90 |
| Noise Cutoff | 400.20 |
| Domain Noise Cutoff | 400.20 |
| Isology Type | equivalog |
| EC Number | 2.3.3.14 |
| HMM Length | 365 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Other |
| Gene Ontology Term | GO:0004410: homocitrate synthase activity molecular_function |
| | GO:0051188: cofactor biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | Sep 9 2005 8:30AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This family consists of the NifV clade of homocitrate synthases, most of which are found in operons for nitrogen fixation. Members are closely homologous to enzymes that include 2-isopropylmalate synthase, (R)-citramalate synthase, and homocitrate synthases associated with other processes. The homocitrate made by this enzyme becomes a part of the iron-molybdenum cofactor of nitrogenase. |
| References | RN [1]
RM 9294461
RT Purification of the Azotobacter vinelandii nifV-encoded homocitrate synthase.
RA Zheng L, White RH, Dean DR.
RL J Bacteriol. 1997 Sep;179(18):5963-6.
RN [2]
RM 12661
RT Molecular cloning and complementation analysis of nifV gene from Frankia EuIK1 strain.
RA Oh CJ, Kim HB, An CS.
RL Mol Cells. 2003 Feb 28;15(1):27-33. |
| Genome Property | GenProp0029: nitrogen fixation (HMM) |
