Accession | TIGR02692 |
Name | tRNA_CCA_actino |
Function | CCA tRNA nucleotidyltransferase |
Trusted Cutoff | 438.80 |
Domain Trusted Cutoff | 438.80 |
Noise Cutoff | 402.00 |
Domain Noise Cutoff | 402.00 |
Isology Type | equivalog |
EC Number | 2.7.7.72 |
HMM Length | 466 |
Mainrole Category | Protein synthesis |
Subrole Category | tRNA and rRNA base modification |
Author | Haft DH |
Entry Date | Nov 16 2005 1:32PM |
Last Modified | Jun 7 2011 2:51PM |
Comment | The enzyme tRNA adenylyltransferase, also called tRNA-nucleotidyltransferase and CCA-adding enzyme, can add or repair the required CCA triplet at the 3'-end of tRNA molecules. Genes encoding tRNA include the CCA tail in some but not all bacteria, and this enzyme may be required for viability. Members of this family represent a distinct clade within the larger family PF01743 (tRNA nucleotidyltransferase/poly(A) polymerase family protein). The example from Streptomyces coelicolor was shown to act as a CCA-adding enzyme and not as a poly(A) polymerase. |
References | DR PFAM; PF01743; PolyA_pol
RN [1]
RM 14645289
RT The Streptomyces coelicolor polynucleotide phosphorylase homologue, and not the putative poly(A) polymerase, can polyadenylate RNA.
RA Sohlberg B, Huang J, Cohen SN.
RL J Bacteriol. 2003 Dec;185(24):7273-8. |