| Accession | TIGR02705 |
| Name | nudix_YtkD |
| Function | nucleoside triphosphatase YtkD |
| Gene Symbol | ytkD |
| Trusted Cutoff | 154.40 |
| Domain Trusted Cutoff | 154.40 |
| Noise Cutoff | 59.90 |
| Domain Noise Cutoff | 59.90 |
| Isology Type | equivalog |
| EC Number | 3.6.1.- |
| HMM Length | 156 |
| Mainrole Category | DNA metabolism |
| Subrole Category | DNA replication, recombination, and repair |
| Gene Ontology Term | GO:0006139: nucleobase-containing compound metabolic process biological_process |
| | GO:0017111: nucleoside-triphosphatase activity molecular_function |
| Author | Haft DH |
| Entry Date | Nov 23 2005 12:39PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | The functional assignment to the proteins of this family is contentious. Reference [2] challenges the findings of reference [1], both in interpretation and in enzyme assay results. This protein belongs to the nudix family and shares some sequence identity with E. coli MutT but appears not to be functionally interchangeable with it. |
| References | DR PFAM; PF00293; NUDIX; hydrolase, NUDIX family
DR SWISSPROT; O35013; Bacillus subtilis
RN [1]
RM 15576788
RT Gene ytkD of Bacillus subtilis encodes an atypical nucleoside triphosphatase member of the Nudix hydrolase superfamily.
RA Xu W, Jones CR, Dunn CA, Bessman MJ.
RL J Bacteriol. 2004 Dec;186(24):8380-4.
RN [2]
RM 14761999
RT The ytkD (mutTA) gene of Bacillus subtilis encodes a functional antimutator 8-Oxo-(dGTP/GTP)ase and is under dual control of sigma A and sigma F RNA polymerases.
RA Ramirez MI, Castellanos-Juarez FX, Yasbin RE, Pedraza-Reyes M.
RL J Bacteriol. 2004 Feb;186(4):1050-9. |
