HMM Summary Page: TIGR02707

Functionbutyrate kinase
Gene Symbolbuk
Trusted Cutoff289.10
Domain Trusted Cutoff289.10
Noise Cutoff129.35
Domain Noise Cutoff129.35
Isology Typeequivalog
EC Number2.7.2.7
HMM Length351
Mainrole CategoryEnergy metabolism
Subrole CategoryFermentation
Gene Ontology TermGO:0006113: fermentation biological_process
GO:0047761: butyrate kinase activity molecular_function
AuthorHaft DH
Entry DateNov 28 2005 4:28PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model represents an enzyme family in which members are designated either butryate kinase or branched-chain carboxylic acid kinase. The EC designation describes an enzyme with relatively broad specificity; gene products whose context suggests a role in metabolism of aliphatic amino acids are likely to act as branched-chain carboxylic acid kinase. The gene typically found adjacent, ptb (phosphate butyryltransferase), likewise encodes an enzyme that may have a broad specificity that includes a role in aliphatic amino acid cabolism.
ReferencesRN [1] RM 10464218 RT Catabolism of branched-chain alpha-keto acids in Enterococcus faecalis: the bkd gene cluster, enzymes, and metabolic route. RA Ward DE, Ross RP, van der Weijden CC, Snoep JL, Claiborne A. RL J Bacteriol. 1999 Sep;181(17):5433-42. DR HAMAP; MF_00542; 28 of 31
Genome PropertyGenProp0910: butyryl-CoA to butyrate, phosphotransbutyrylase pathway (HMM-CLUST)