HMM Summary Page: TIGR02734

Functionphytoene desaturase
Gene SymbolcrtI
Trusted Cutoff238.10
Domain Trusted Cutoff238.10
Noise Cutoff165.95
Domain Noise Cutoff165.95
Isology Typesubfamily
EC Number1.14.99.-
HMM Length504
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryOther
Gene Ontology TermGO:0016117: carotenoid biosynthetic process biological_process
GO:0016166: phytoene dehydrogenase activity molecular_function
AuthorHaft DH
Entry DateDec 14 2005 1:01PM
Last ModifiedFeb 14 2011 3:27PM
CommentPhytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (crtP and crtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI. Most members of this family, part of the larger Pfam family PF01593, which also contains amino oxidases, are CrtI itself; it is likely that all members act on either phytoene or on related compounds such as dehydrosqualene, for carotenoid biosynthesis.
Genome PropertyGenProp0758: lycopene biosynthesis from IPP (HMM)
GenProp0758: lycopene biosynthesis from IPP (HMM)