|Function||type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB|
|Domain Trusted Cutoff||132.00|
|Domain Noise Cutoff||102.80|
|Entry Date||Dec 17 2005 11:12AM|
|Last Modified||Nov 21 2011 3:46PM|
|Comment||This protein is part of a large group of proteins involved in conjugative transfer of plasmid DNA, specifically the F-type system. This protein has been predicted to contain a thioredoxin fold, contains a conserved pair of cysteines and has been shown to function as a thiol disulfide isomerase by complementation of an Ecoli DsbA defect . The protein is believed to be involved in pilin assembly . The protein is closely related to TraF (TIGR02739) which is somewhat longer, lacks the cysteine motif and is apparently not functional as a disulfide bond isomerase.|
RM PMID: 16321931
RA Elton TC, Holland SJ, Frost LS, Hazes B.
RT F-like type IV secretion systems encode proteins with thioredoxin folds that are putative DsbC homologues.
RL J Bacteriol. 2005 Dec;187(24):8267-77.
RM PMID: 16138100
RA Frost LS, Leplae R, Summers AO, Toussaint A.
RT Mobile genetic elements: the agents of open source evolution.
RL Nat Rev Microbiol. 2005 Sep;3(9):722-32.|
|Genome Property||GenProp0484: F-type conjugation system (type IV secretion) specific components (HMM)|
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