HMM Summary Page: TIGR02755
| Accession | TIGR02755 |
| Name | TraX_Ftype |
| Function | type-F conjugative transfer system pilin acetylase TraX |
| Gene Symbol | traX |
| Trusted Cutoff | 149.35 |
| Domain Trusted Cutoff | 149.35 |
| Noise Cutoff | 104.70 |
| Domain Noise Cutoff | 104.70 |
| Isology Type | equivalog |
| EC Number | 2.3.1.- |
| HMM Length | 224 |
| Author | Selengut J |
| Entry Date | Dec 22 2005 9:26AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | TraX is responsible for the acetylation of the F-pilin TraA during conjugative plasmid transfer. The purpose of this acetylation is unclear, but the reported transcriptional regulation of TraX may indicate that it is involved in the process of pilu extension/retraction [1,2,3]. |
| References | RN [1] RM PMID: 8444800 RA Moore D, Hamilton CM, Maneewannakul K, Mintz Y, Frost LS, Ippen-Ihler K. RT The Escherichia coli K-12 F plasmid gene traX is required for acetylation of F pilin. RL J Bacteriol. 1993 Mar;175(5):1375-83. RN [2] RM PMID: 7768788 RA Maneewannakul K, Maneewannakul S, Ippen-Ihler K. RT Characterization of traX, the F plasmid locus required for acetylation of F-pilin subunits. RL J Bacteriol. 1995 Jun;177(11):2957-64. RN [3] RM PMID: 16138100 RA Frost LS, Leplae R, Summers AO, Toussaint A. RT Mobile genetic elements: the agents of open source evolution. RL Nat Rev Microbiol. 2005 Sep;3(9):722-32. |
| Genome Property | GenProp0484: F-type conjugation system (type IV secretion) specific components (HMM) |