|Function||type-F conjugative transfer system secretin TraK|
|Domain Trusted Cutoff||124.00|
|Domain Noise Cutoff||63.05|
|Entry Date||Dec 22 2005 9:52AM|
|Last Modified||Feb 14 2011 3:27PM|
|Comment||The TraK protein is predicted to interact with the TraV and TraB proteins as part of the scaffold which extends from the inner membrane, through the periplasm to the cell envelope and through which the F-type conjugative pilus passes. TraK is homologous to the P-type IV secretion system protein TrbG, the Ti-type protein VirB9 and the I-type TraN protein. The protein is related to the secretin family especially the HrcC subgroup of the type III secretion system. The protein is hypothesized to oligomerize to form a ring structure akin to other secretins [1,2,3].|
RM PMID: 11722740
RA Harris RL, Hombs V, Silverman PM.
RT Evidence that F-plasmid proteins TraV, TraK and TraB assemble into an envelope-spanning structure in Escherichia coli.
RL Mol Microbiol. 2001 Nov;42(3):757-66.
RM PMID: 12855161
RA Lawley TD, Klimke WA, Gubbins MJ, Frost LS.
RT F factor conjugation is a true type IV secretion system.
RL FEMS Microbiol Lett. 2003 Jul 15;224(1):1-15.
RM PMID: 16138100
RA Frost LS, Leplae R, Summers AO, Toussaint A.
RT Mobile genetic elements: the agents of open source evolution.
RL Nat Rev Microbiol. 2005 Sep;3(9):722-32.|
|Genome Property||GenProp0485: F and P-type conjugation systems (type IV secretion), common components (HMM)|
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