HMM Summary Page: TIGR02758

Functiontype IV conjugative transfer system pilin TraA
Gene SymboltraA
Trusted Cutoff76.55
Domain Trusted Cutoff76.55
Noise Cutoff39.70
Domain Noise Cutoff39.70
Isology Typeequivalog
HMM Length98
AuthorSelengut J
Entry DateDec 22 2005 3:50PM
Last ModifiedFeb 14 2011 3:27PM
CommentTraA is the single structural subunit of the pilus found in type IV conjugative transfer systems. This family is generally found in gammaproteobacteria. The pilins show considerable heterogeneity among the different conjugative plasmit types. All of them however contain an N-terminal part which is cleaved off by a leader peptidase (LepB, or similar) to result in a 68-78 amino acid product. Pilins may be further processed by acetylation (in F-like systems by the TraX protein) or by cyclization (in P-like systems by the TraF protein) [1].
ReferencesRN [1] RM PMID: 7768788 RA Maneewannakul K, Maneewannakul S, Ippen-Ihler K. RT Characterization of traX, the F plasmid locus required for acetylation of F-pilin subunits. RL J Bacteriol. 1995 Jun;177(11):2957-64.
Genome PropertyGenProp0485: F and P-type conjugation systems (type IV secretion), common components (HMM)