| Accession | TIGR02787 |
| Name | codY_Gpos |
| Function | GTP-sensing transcriptional pleiotropic repressor CodY |
| Gene Symbol | codY |
| Trusted Cutoff | 267.20 |
| Domain Trusted Cutoff | 267.20 |
| Noise Cutoff | 133.85 |
| Domain Noise Cutoff | 133.85 |
| Isology Type | equivalog |
| HMM Length | 251 |
| Mainrole Category | Regulatory functions |
| Subrole Category | DNA interactions |
| Gene Ontology Term | GO:0003700: sequence-specific DNA binding transcription factor activity molecular_function |
| | GO:0005525: GTP binding molecular_function |
| | GO:0006355: regulation of transcription, DNA-dependent biological_process |
| | GO:0016597: amino acid binding molecular_function |
| Author | Haft DH |
| Entry Date | Jan 13 2006 12:20PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This model represents the full length of CodY, a pleiotropic repressor in Bacillus subtilis and other Firmicutes (low-GC Gram-positive bacteria) that responds to intracellular levels of GTP and branched chain amino acids. The C-terminal helix-turn-helix DNA-binding region is modeled by PF08222 in Pfam. |
| References | DR PFAM; PF06018; CodY; CodY GAF-like domain
DR PFAM; PF08222; HTH_CodY; CodY helix-turn-helix domain
DR SWISSPROT; P39779; Bacillus subtilis
RN [1]
RM 15802253
RT CodY, a global regulator of stationary phase and virulence in Gram-positive bacteria.
RA Sonenshein AL.
RL Curr Opin Microbiol. 2005 Apr;8(2):203-7.
DR HAMAP; MF_00621; 70 of 70 |
