HMM Summary Page: TIGR02819
| Accession | TIGR02819 |
| Name | fdhA_non_GSH |
| Function | formaldehyde dehydrogenase, glutathione-independent |
| Gene Symbol | fdhA |
| Trusted Cutoff | 636.95 |
| Domain Trusted Cutoff | 636.95 |
| Noise Cutoff | 425.15 |
| Domain Noise Cutoff | 425.15 |
| Isology Type | equivalog |
| EC Number | 1.2.1.46 |
| HMM Length | 397 |
| Mainrole Category | Central intermediary metabolism |
| Subrole Category | One-carbon metabolism |
| Gene Ontology Term | GO:0018467: formaldehyde dehydrogenase activity molecular_function |
| GO:0046292: formaldehyde metabolic process biological_process | |
| Author | Haft DH |
| Entry Date | Feb 8 2006 5:17PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this family represent a distinct clade within the larger family of zinc-dependent dehydrogenases of medium chain alcohols, a family that also includes the so-called glutathione-dependent formaldehyde dehydrogenase. Members of this protein family have a tightly bound NAD that can act as a true cofactor, rather than a cosubstrate in dehydrogenase reactions, in dismutase reactions for some aldehydes. The name given to this family, however, is formaldehyde dehydrogenase, glutathione-independent. |