| Accession | TIGR02820 |
| Name | formald_GSH |
| Function | S-(hydroxymethyl)glutathione synthase |
| Gene Symbol | gfa |
| Trusted Cutoff | 234.55 |
| Domain Trusted Cutoff | 234.55 |
| Noise Cutoff | 135.65 |
| Domain Noise Cutoff | 135.65 |
| Isology Type | equivalog |
| EC Number | 4.4.1.22 |
| HMM Length | 182 |
| Mainrole Category | Cellular processes |
| Subrole Category | Detoxification |
| Gene Ontology Term | GO:0046292: formaldehyde metabolic process biological_process |
| | GO:0051907: S-(hydroxymethyl)glutathione synthase activity molecular_function |
| Author | Haft DH |
| Entry Date | Feb 9 2006 10:08PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | The formation of S-(hydroxymethyl)glutathione synthase from glutathione and formaldehyde occurs naturally, but this enzyme speeds its formation in some species as part of a pathway of formaldehyde detoxification. |
| References | RN [1]
RM 11741920
RT A glutathione-dependent formaldehyde-activating enzyme (Gfa) from Paracoccus denitrificans detected and purified via two-dimensional proton exchange NMR spectroscopy.
RA Goenrich M, Bartoschek S, Hagemeier CH, Griesinger C, Vorholt JA.
RL J Biol Chem. 2002 Feb 1;277(5):3069-72.
DR HAMAP; MF_00723; 13 of 13 |
| Genome Property | GenProp0562: formaldehyde detoxification, glutathione-dependent (HMM) |
