HMM Summary Page: TIGR02859

FunctionRNA polymerase sigma-H factor
Gene SymbolsigH
Trusted Cutoff294.80
Domain Trusted Cutoff294.80
Noise Cutoff82.50
Domain Noise Cutoff82.50
Isology Typeequivalog
HMM Length198
Mainrole CategoryTranscription
Subrole CategoryTranscription factors
Gene Ontology TermGO:0006352: transcription initiation, DNA-dependent biological_process
GO:0016987: sigma factor activity molecular_function
GO:0042173: regulation of sporulation resulting in formation of a cellular spore biological_process
AuthorHaft DH
Entry DateMar 3 2006 12:22AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are RNA polymerase sigma-H factor for sporulation in endospore-forming bacteria. This protein is also called Sigma-30 and SigH. Although rather close homologs in Listeria score above the noise cutoff to this HMM, Listeria does not form spores and the role of the related sigma factor in that genus is in doubt.
ReferencesDR SWISSPROT; P17869; Bacillus subtilis RN [1] RM 3277943 RT Bacillus sporulation gene spo0H codes for sigma 30 (sigma H). RA Dubnau E, Weir J, Nair G, Carter L 3rd, Moran C Jr, Smith I. RL J Bacteriol. 1988 Mar;170(3):1054-62.
Genome PropertyGenProp0610: endospore formation marker gene set (HMM)